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Wegovy vs Saxenda in South Africa

How Wegovy (semaglutide) and Saxenda (liraglutide) compare on cost, dosing and what they're approved for.

	Wegovy	Saxenda
Active ingredient	semaglutide	liraglutide
How often	once weekly	once daily
Monthly cost	R1 800–R3 700	R2 800–R5 400
Approved for	Registered specifically for weight management (higher-dose semaglutide)	Registered for weight management
Medical aid	Not typically covered — obesity is not classified as a chronic condition by most SA schemes	Not typically covered for weight loss

Wegovy

Same active ingredient as Ozempic (semaglutide) but dosed and registered for weight loss, titrating up to 2.4 mg weekly. Novo Nordisk recently cut its SA prices, making the starting doses more competitive.

Wegovy details

Saxenda

The daily liraglutide pen — the longest-available weight-loss GLP-1 in SA, now often overtaken by weekly options. A 6 mg/mL pen is around R2 727, and a typical month works out near R4 600.

Saxenda details

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FAQ

Frequently asked questions

Is Wegovy or Saxenda better for weight loss?

Both can support weight loss, but suitability is individual. Wegovy uses semaglutide and Saxenda uses liraglutide. Your doctor will recommend based on your health and goals.

What is the price difference between Wegovy and Saxenda in South Africa?

Wegovy is indicatively R1 800–R3 700 a month, while Saxenda is R2 800–R5 400. Confirm current pharmacy prices.

Can I switch from Wegovy to Saxenda?

Only under medical supervision. A doctor will manage the change in dose and timing safely.

Sources: South African Health Products Regulatory Authority (SAHPRA) registration data, the approved package inserts, and public pharmacy price listings. Last reviewed 2026-05-30. No information here is medical advice.