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Wegovy vs Mounjaro in South Africa

How Wegovy (semaglutide) and Mounjaro (tirzepatide) compare on cost, dosing and what they're approved for.

	Wegovy	Mounjaro
Active ingredient	semaglutide	tirzepatide
How often	once weekly	once weekly
Monthly cost	R1 800–R3 700	R2 800–R5 500
Approved for	Registered specifically for weight management (higher-dose semaglutide)	Dual-action (GIP/GLP-1) for type 2 diabetes and weight management
Medical aid	Not typically covered — obesity is not classified as a chronic condition by most SA schemes	Generally not covered for weight loss; diabetes use may qualify on application

Wegovy

Same active ingredient as Ozempic (semaglutide) but dosed and registered for weight loss, titrating up to 2.4 mg weekly. Novo Nordisk recently cut its SA prices, making the starting doses more competitive.

Wegovy details

Mounjaro

The newer tirzepatide option, often cited for strong results. Distributed by Aspen in SA as single-dose vials (a KwikPen is under SAHPRA evaluation); a typical month is about R4 000 for four vials.

Mounjaro details

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FAQ

Frequently asked questions

Is Wegovy or Mounjaro better for weight loss?

Both can support weight loss, but suitability is individual. Wegovy uses semaglutide and Mounjaro uses tirzepatide. Your doctor will recommend based on your health and goals.

What is the price difference between Wegovy and Mounjaro in South Africa?

Wegovy is indicatively R1 800–R3 700 a month, while Mounjaro is R2 800–R5 500. Confirm current pharmacy prices.

Can I switch from Wegovy to Mounjaro?

Only under medical supervision. A doctor will manage the change in dose and timing safely.

Sources: South African Health Products Regulatory Authority (SAHPRA) registration data, the approved package inserts, and public pharmacy price listings. Last reviewed 2026-05-30. No information here is medical advice.