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Mounjaro vs Saxenda in South Africa

How Mounjaro (tirzepatide) and Saxenda (liraglutide) compare on cost, dosing and what they're approved for.

	Mounjaro	Saxenda
Active ingredient	tirzepatide	liraglutide
How often	once weekly	once daily
Monthly cost	R2 800–R5 500	R2 800–R5 400
Approved for	Dual-action (GIP/GLP-1) for type 2 diabetes and weight management	Registered for weight management
Medical aid	Generally not covered for weight loss; diabetes use may qualify on application	Not typically covered for weight loss

Mounjaro

The newer tirzepatide option, often cited for strong results. Distributed by Aspen in SA as single-dose vials (a KwikPen is under SAHPRA evaluation); a typical month is about R4 000 for four vials.

Mounjaro details

Saxenda

The daily liraglutide pen — the longest-available weight-loss GLP-1 in SA, now often overtaken by weekly options. A 6 mg/mL pen is around R2 727, and a typical month works out near R4 600.

Saxenda details

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FAQ

Frequently asked questions

Is Mounjaro or Saxenda better for weight loss?

Both can support weight loss, but suitability is individual. Mounjaro uses tirzepatide and Saxenda uses liraglutide. Your doctor will recommend based on your health and goals.

What is the price difference between Mounjaro and Saxenda in South Africa?

Mounjaro is indicatively R2 800–R5 500 a month, while Saxenda is R2 800–R5 400. Confirm current pharmacy prices.

Can I switch from Mounjaro to Saxenda?

Only under medical supervision. A doctor will manage the change in dose and timing safely.

Sources: South African Health Products Regulatory Authority (SAHPRA) registration data, the approved package inserts, and public pharmacy price listings. Last reviewed 2026-05-30. No information here is medical advice.